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Opium's Family Tree

(Please note, this is not an exhaustive list, but it should give you a good overview.) There is quite a list of generic and individual brand names; this can be quite confusing, as they tend to overlap. I am not a chemist, so in this case, it is, “rocket science” so to speak.

After reading this section, you will have a basic education of what should be called “Narcotics 101”. I want to point out a few things in the chart. First, if you look at the purple shaded arrow pointing from Morphine Base to a box entitled, Illicit Market, which then points further down to still another box entitled Heroin. You can see I have indicated that morphine is made into heroin. This is through a process in which morphine is synthesized using acetic anhydride making diacetylmorphine (heroin). Around the late 1800’s, there were two basic analgesics, willow bark and morphine. Instead of trying to invent a brand new drug, scientists thought it would better serve us to to improve what analgesics we had. *[In 1874 English researcher, C.R. Wright synthesized morphine and came up with diacetylmorphine. Heinrich Dreser, of the Bayer Company in Elberfeld, Germany, noticed that diacetylmorphine was more potent than morphine. Bayer registered Heroin (meaning heroic treatment from the German word heroisch) as a trademark. From 1898 through to 1910, it was marketed as a non-addictive morphine substitute and was put into cough medicines for children. As with aspirin (synthesized willow bark in its crude form)] 1

The Germans in WWII originally made METHADONE (large green circle) from coal. During the war, supply lines to the Near East where cut off due to the Allies war effort. The Germans had to come up with a much-needed potent analgesic and coal was abundant. Today, it’s a synthesized opioid, manufactured in a more conventional way in drug laboratories. I should also note 2 here that in the chemistry of opiates (or opioids) they have what is called the morphine rule. This is where the molecular structure is similar even though the compound has been altered. Most all narcotic analgesics follow this rule, with some exceptions. Methadone is an analogue that follows the morphine rule, but is considered an open chained opioid analgesic. PROPOXEPHENE, indicated in the chart underneath the green methadone circle, is lesser in strength then that of Methadone, although closely related. These both have similar compounds of the same basic drug, and like other narcotics, come with different name brands. Both methadone and propoxephene are both noted for their long lasting effect, which is why they are used in treating heroin and other opiate addicts as you may well know.

In the diagram, you will see the different colored blocks of heroin. After heroin is taken from morphine, it is in its purest form called NUMBER #4 HEROIN. Number four heroin is then cut with many substances to dilute its strength and to optimize the dollar amount. Pure heroin is so strong that you could use a miniscule amount and it would cause sudden death. Raw opium’s value is increased dramatically when processed into heroin (see chart below). The more cut, the more the dollar amount is stretched. Heroin is then made into three main categories, China White, Mexican Brown, and Black Tar. Today heroin is illegal to sell or possess even for doctors. It is a Schedule I under the Controlled Substance Act.4 In 2006, despite the “war on drugs” heroin traffic is alive and well. Even though it is illegal, it is a very lucrative business. It is stronger and more available than ever before in our nation’s history. By studying the history of heroin over the years along with the latest statistics, I have concluded that it is virtually impossible to stop its manufacture, distribution, possession and use. It continues to be a growing problem.

 

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Click on the Above Image to Enlarge or Click Link for PowerPoint Slide: Opium's Family Tree

 

Morphine Molecule                                                            Heroin Molecule

 

 

 

 

 

 

 

 

 

Opium Tolerance Level Chart
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